Can ALS (Amyotrophic Lateral Sclerosis) be Approached from Unconventional Angles?
About ALS ALS (Amyotrophic Lateral Sclerosis) is a motor neurone disease, and a wickedly complex illness. The root cause (or something very close to it) seems to be malfunction in mitochondria, the energy factories of the cell. This is somehow related to damage to the membranes surrounding mitochondria. Damaged mitochondria in motor neurons and muscles "leak" energy as heat rather than producing useful ATP for the cell. This is dangerous, since the body must burn more fuel to compensate. But doing so further stresses already malfunctioning mitichondria. All this ultimately creates an energy deficit large enough that cells begin to fail to carry out basic internal maintenance. Cells then begin to deteriorate and die-off, starting at the junction where nerve meet muscle (neuro-muscular junction, or NMJ), and progressing backward from NMJ sites towards the central nervous system and brain. Based on personal conviction, if I had to start with one therapy, I would start with Got...